Predicting DNA hybridization kinetics from sequence
نویسندگان
چکیده
منابع مشابه
Predicting DNA hybridization kinetics from sequence.
Hybridization is a key molecular process in biology and biotechnology, but so far there is no predictive model for accurately determining hybridization rate constants based on sequence information. Here, we report a weighted neighbour voting (WNV) prediction algorithm, in which the hybridization rate constant of an unknown sequence is predicted based on similarity reactions with known rate cons...
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ژورنال
عنوان ژورنال: Nature Chemistry
سال: 2017
ISSN: 1755-4330,1755-4349
DOI: 10.1038/nchem.2877